Optimizing the Granulation Process: A Key to Enhanced Pharma Manufacturing

Introduction Granulation is a critical step in the pharmaceutical manufacturing process, influencing the quality and efficacy of the final product. At Tantrasoft Solutions, our cutting-edge E-Granulation System is engineered to optimize every phase of the granulation process, from wet to dry granulation, ensuring superior product quality and increased operational efficiency.

Understanding Granulation Challenges Granulation involves forming granules by adding a binding agent to powders, which enhances the flow of the powder mix and prevents segregation. This process is essential for the consistent quality and manufacturability of tablets and capsules. However, granulation can present challenges such as maintaining consistent granule size, optimizing moisture content, and ensuring uniform mixing.

Key Features of the E-Granulation System Our E-Granulation System incorporates several features designed to address these challenges and streamline your granulation process:

  • Automated Ingredient Sifting and Mixing: Ensures precise sifting of raw materials and thorough mixing of binding agents, as outlined in your specific product recipe .
  • Real-Time Process Monitoring: Tracks critical parameters such as impeller and chopper speed during dry mixing, and monitors ampere readings to determine the granulation endpoint .
  • Quality Assurance Checks: Includes checkpoints for verifying the dissolution of binding agents and the integrity of granulation equipment, ensuring compliance with quality standards .

Enhanced Control with Wet and Dry Granulation The system is adept at both wet and dry granulation:

  • Wet Granulation: Controls the addition and mixing of binders, optimizes drying times, and ensures the integrity of sieves and screens .
  • Dry Granulation: Monitors roller compactor parameters and blending operations to ensure uniformity and optimal compression .

Success Stories Numerous top pharmaceutical companies have implemented our E-Granulation System, achieving remarkable improvements in product consistency, manufacturing speed, and compliance. Clients such as Adcock Ingram and Sun Pharma have seen enhanced process control and reduced batch-to-batch variation .

Conclusion By optimizing the granulation process with Tantrasoft’s E-Granulation System, pharmaceutical manufacturers can achieve higher efficiency, better product quality, and compliance with stringent regulatory standards. Embrace the future of pharmaceutical manufacturing with solutions that pave the way for innovation and success.


(+91) 7506029981


A-403, Mathuria Apts, Sir M.V.Road, Andheri (East), Mumbai – 400069.

Copyright © 2024 Tantrasoft Solutions